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DRUG FREE | NON-INVASIVE INTERX TECHNOLOGY

As the InterX is impedance sensitive, it can be applied directly to the skin and moved around over the skin without conductive gels. This allows the user to be able to assess the impedance of the skin to identify and target optimal treatment points. This has led to the development of the three step protocol of almost every InterX treatment: Scan, Target, Dynamic.
 
SCAN
 
Identify optimal treatment points
 
TARGET
 
Deliver focused, high amplitude stimulation
 
DYNAMIC
 
Perform therapeutic exercise while treating points of pain
 
INTERX® THERAPY IS SAFE, DRUG FREE AND NON-INVASIVE
 
InterX® is safe, drug free and non-invasive. Hand-held and battery operated, the InterX® products use advanced Interactive Neurostimulation technology to deliver treatment for a variety of medical conditions. The InterX® products have proven effective for: Acute and chronic pain relief and the resulting increase in range of motion, neuropathic and nociceptive pain, reducing rehabilitation times from sports injuries and other acute trauma.
 
WHAT MAKES INTERX DIFFERENT
 
There are four main areas where InterX is different and it requires an awareness of all of them and how they interrelate to really understand why this powerful technology can be so effective. The interactive nature of the stimulation allows for a unique, evidence-based application that optimizes treatment parameters and thus achieves consistently good results across a broad range of conditions.
  • The Technology
  • The Application
  • Optimization of Parameters
  • The Results

InterX® therapy is safe, drug free and non-invasive. Hand-held and battery operated, the InterX® products use advanced Interactive Neurostimulation technology to deliver treatment for a variety of medical conditions.

The InterX® products carry the European CE mark and is 510(k) cleared by the US FDA as a pain management device. The InterX® products have been safely and effectively used to treat thousands of patients throughout the world.

THE RESULTS

InterX has been clinically proven to be effective on very complex chronic conditions that had not responded to any other treatment as well acute post-surgical orthopedic pain which has proven very difficult to treat with neurostimulation in the past. While the protocols for each of these applications may be very different, the technology allows for the treatment to be customized for every patient and their condition to ensure optimal results. Many patients are amazed by the results of their InterX treatment and many learned and experienced therapists believe InterX is the most effective and consistent modality they have ever used and they benefit from the fact that there is scientific and clinical evidence to support its application.

View the remarkable case studies here.

TEN REASONS TO CHOOSE INTERX OVER OTHER STIMULATION DEVICES FOR PAIN

1. Patented Neurostimulation System for pain relief: 5002 and 1000 devices plus all the electrode attachments are part of a broad patent.

2. Flex Array pads are the only patented technology for self directing, impedance seeking, stainless steel electrode pads that can be cleaned and used between patients, extremely durable.

3. Unique design of the device head allows for greatest skin contact with uniform conduction.

4. Multiple features make it easy to use to get fast results see device technology

5. Simple treatment techniques for acute pain yield incredible results see training

6. Relief from the most stubborn or severe chronic pain is achieved through training by the InterX Therapy practitioners.

7. Established InterX Therapy Clinic since 2008 with proven treatment methods.

8. Professional and Personal training available by InterX Therapy licensed practitioners

9. InterX is chosen by the military, professional sports teams in the USA and International, College Teams, High Schools, Ninja Warriors, airline pilots because it is non drug, non invasive and great results.

10. Chosen by Physical Therapists, Occupational Therapists, Chiropractors, Athletic Trainers, Medical Doctors across the USA and Internationally.

FAQs

Specificity of the Stimulation (Scan)

There are two generally accepted theories for the mechanism of action of electrical stimulation devices; The Gate Control Theory and the Stimulation of the release of endogenous opioids. The exact mechanism of InterX is not yet fully understood and there appear to be a number of mechanisms at work based on the applications used and clinical outcomes that are observed. The amplitude of the stimulation is sufficient to cause endogenous opioid release and this may explain the immediacy of results experienced with InterX. Often pain relief lasts long after the treatment is over which hints at a neuropeptide/cytokine cascade effect and a CNS response. Clinical trials have shown reduction of inflammation and improved tissue formation with InterX stimulation which is also supported with anecdotal evidence.

How much does InterX cost and will my insurance cover it?

Treatment is eligible for reimbursement through individual clinics and practitioners, but the device is not covered under most insurances.
The InterX does not mask pain. If that were the case pain would return soon after the treatment ended. InterX is committed to clinical trials to research the sustained relief as well as reduction of inflammation that is observed following InterX therapy.


InterX® therapy will be delivered by a trained practitioner, often in a clinical or sports setting. Typical treatments last from 15 to 30 minutes and the procedure will involve applying the hand-held device or its remote probes directly to the skin. Treatment will be on the skin of the involved area, and often non-involved areas on the opposite side of the body or the back.

The device may be held stationary or moved along the skin in sweeping motions, depending on the chosen mode of treatment. The sensation the patient may feel a tickling or vibrating sensation, or it may feel like a prickling or fine needling sensation. Some people are more sensitive than others to neurostimulation. The way your body responds to the treatment may not be the same as the next person. There is the potential that people who are very sensitive to neurostimulation may temporarily experience discomfort or light-headedness.

The number of treatments needed will depend upon the severity of your condition and how long you have had the problem. Quite often patients feel relief after 1“ 3 treatments but complex long standing conditions may require more effort.

The InterX® products can be applied independently as a full treatment or concurrently with existing therapy (physical or occupational) activities to meet and enhance therapy goals. The number of visits and duration of treatment is highly dependent upon the complexity of the patients medical history and condition, and whether the InterX® product is used independently or as a concurrent treatment. Case examples:
Acute minor ankle sprain may only require one 15-minute session for a healthy individual when InterX® therapy is applied as a concurrent treatment to active therapy.
Chronic low back pain and a complicated medical history may experience a 30-minute treatment and require 3-4 treatments per week for 2-3 weeks.
Post-operative ACL repair may experience a 15-minute InterX® treatment multiple times before each physical therapy session.
Once therapy has begun, it is important to complete the full, recommended treatment course in order to experience optimum relief from symptoms. Neurostimulation activates a physical response, which may increase the sensation of pain for a few hours. Adherence to the full course of treatment will minimize symptoms that a patient may experience during the natural healing process.

Yes, there is a one year warranty on all InterX devices and electrodes. Extended warranty options are available.

InterX® therapy is a safe, non-invasive treatment that can be used on patients of all ages. Consult your physician regarding the InterX® treatment approach that is best for your individual medical condition. To InterXs knowledge, there have been no reported cases of severe injury due to the use of the InterX® products. However, caution should be taken when using neurostimulation devices as they may interfere with other electrical medical devices.

InterX® therapy is a safe, non-invasive treatment that can be used on patients of all ages. Patients should consult their physician regarding the InterX® treatment approach that is best for an individual medical condition.

Although it introduces electrical impulses into the body, the InterX® products achieve results through an approach that is very different to conventional neurostimulation.

InterXs management has extensive experience in the healthcare industry and is committed to providing service and products that improve the quality of life for patients and athletes receiving treatment with its products.

Available upon request are numerous resources and references regarding the use and study of InterX® therapy.

Contact Us For additional information or supporting documentation

 

No, the Flexible Array electrode allows for unattended treatment. We recommend scanning the area first with the main device, then targeting the area with the flexible array during which time you can direct the patient to perform exercises or you can continue the treatment unattended.

InterX is an advanced form of Neurostimulation that integrates into existing treatment programs to enable enhanced results with both acute and chronic conditions. InterX is FDA cleared for acute and chronic pain relief and pain management.

The InterX products are effective for:

  • Acute and chronic pain relief and the resulting increase in range of motion
  • Neuropathic and nociceptive pain
  • Reducing rehabilitation times from sports injuries and other acute trauma
  • Muscle relaxation, reducing muscle cramps and spasms
  • Enhancing neuromuscular re-education

Scan The treatment area is scanned using the InterX device to identify specific areas of low impedance. These are optimal treatment points for InterX stimulation. The scanning can be done either by sliding the device over the skin or by placing the device and taking numerical measurements.

Target These areas of low impedance are then targeted with very specific stimulation. The interactive stimulation adjusts constantly in response to changes in the electrophysiology of the tissue. This specific, dynamic stimulation is unique to this technology.

Dynamic If appropriate, the patient is moved through a series of positions, stretches or exercises while stimulation is applied to points of pain. The portability and ease of application make this a very quick and effective application where neuromuscular and proprioceptive re-education can be combined with interactive neuro-stimulation for enhanced results.

The time needed for treatment can vary but averages approx. 15 minutes. Very short treatments can be used on the sidelines of a sports game taking only a few minutes. When treating more difficult chronic conditions, the session may last up to 30 minutes as there is a larger area of the body to scan when incorporating neurologically related areas.

Product Review: Non-Invasive Neuromodulation for the Treatment of the Most Difficult Pain Conditions. (2020) Inside today’s intelligent devices and an applied example using the InterX.

Transcutaneous electrical nerve stimulation (TENS) can reduce postoperative analgesic consumption. (2003), A meta-analysis with assessment of optimal treatment parameters for postoperative pain. Jan Magnus Bjordala,*, Mark I. Johnsonb, Anne Elisabeth Ljunggreena

NRG Sinusitus Study (2008), The Effects of Treatment of an Interactive Cutaneous Neurostimulator on Recurrent Sinusitis. Gerhard Maale, MD Janice Walker, OTR

NRG Ankle Study (2008), The effects of InterX treatment on Pain and Oedeme during Post Surgical Rehabilitation following Internal Fixation of Unstable Bimalleolar Ankle Fractures. I.G. Gorodetskyi, A.I. Gorodnichenko, P.S. Tursin, V.K. Reshetnyak, O.N. Uskov

The Skin as a Neuroimmunoendocrine Organ (2004),Neuronal Control of Skin Function:The Skin as a Neuroimmunoendocrine Organ .Dirk Roosterman, Tobias Goerge, Stefan W. Schneider, Nigel W. Bunnett and Martin Steinhoff

Neuropathic pain (2004), Contemporary Management of Neuropathic Pain for the Primary Care Physician. HSIUPEI CHEN, MD; TIM J. LAMER, MD; RICHARD H. RHO, MD; KENNETH A. MARSHALL, MD;B. TODD SITZMAN, MD; SALIM M. GHAZI, MD; AND RANDALL P. BREWER, MD

Mechanisms of TENS (2003), Transcutaneous ElectricalNerve Stimulation: Basic Science Mechanismsand Clinical Effectiveness. Kathleen A. Sluka* and Deirdre Walsht

MCL Sheep study abstract (2010), Non-invasive Interactive Neurostimulation (InterX ) as an adjunct in pain control for patients following Total Knee and Total Hip Arthroplasty: a Randomized Placebo Controlled Trial. A. Pedadda, MD G. Maale, MD

Knee Hip poster (2010), Non-invasive Interactive Neurostimulation (InterX ) as an adjunct in pain control for patients following Total Knee and Total Hip Arthroplasty: a Randomized Placebo Controlled Trial. A. Pedadda, MD G. Maale, MD

InterX vs TENS Poster

InterX vs TENS(2010), NON-INVASIVE INTERACTIVE NEUROSTIMULATION (INTERX®) ELICITS SIGNIFICANTLY GREATER PHYSIOLOGICAL RESPONSE THAN TENS: LYMPHOCYTE METABOLISM AND CYTOKINE PRODUCTION . Gail Pyne-Geithman, D.Phil.*, Joseph F. Clark, Ph.D.

IASP 2010  LBP InterX Clinic(2010), INTERX DEVICE FOR THE TREATMENT OF CHRONIC INTRACTABLE LOWER BACK PAIN: A PILOT STUDY. Janice Walker OTR, Dr Zulia Valeyeva Frost MD

IASP 2010 CRPS-MKTG-0202010), INTERX THERAPY, A NEW APPROACH TO TREATING CRPS: A CASE HISTORY. Complex regional pain syndrome is described as a disease of the autonomic nervous system. Janice Walker OTR, Paul Magee

Bruise case study(2009), InterX Therapy was applied 8 days after trauma. Two treatments were applied in the 24 hour period following the eighth day after initial trauma.

Blood study(2009),Changes in Lymphocyte Metabolism, Genexpression and Cytokine production following Transdermal Interactive Neurostimulation: indicators of Connective Tissue Healing and Anti-inflammatory activity

InterX Brochure (2008), by Dr. Zulia Valeyeva-Frost

Cutaneous patterns of sympathetic activity in clinical abnormalities of the musculosceletal system(1964), Irvin M.Korr, H.M.Wright, J.A. Chace

The Evaluation of Electrodermal Properties in the Identification of Myofascial Trigger PointsSarah P. Shultz, MEd, Jeffrey B. Driban, MEd, Charles B. Swanik, PhD

An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle, Jay P. Shah, Terry M. Phillips, Jerome V. Danoff and Lynn H. Gerber

Fall of Skin Impedance in Bone and Joint PainFujita Takuo, Fujii Yoshio¦

A Cascade of cytokines mediates mechanical inflammatory hypernocyception in mice T.M.Cunha

The Effects of Non-Invasive Interactive Neurostimulation Therapy on Pain and Oedema during Post Surgical Rehabilitation following Internal Fixation of Unstable Bimalleolar Ankle Fractures I.G. Gorodetskyi, A.I. Gorodnichenko, P.S. Tursin, V.K. Reshetnyak, O.N. Uskov

Case Study Reflex Sympathetic Dystrophy(RSD)/Complex Regional Pain Syndrome(CRPS) NRG

ASP 2010 Abstract  PPH TKRInterX as an adjunct for pain control in patients following total knee replacement, Dr Ashok K.Nigam, Dr Zulia-Valayeva Frost, Drena Taylor

ASP 2010 InterX Hip Abstract, InterX as an adjunct for pain control in patients following total hip replacement, Dr. Arvind V Peddada, Dr Gerhard Maale

ASP 2010  InterX Knee Abstract, InterX as an adjunct for pain control in patients following total knee arthroplasty, Dr. Arvind V Peddada, Dr Gerhard Maale

ASP Abstract 2010 “ InterX vs Baseline, Changes in lymphocyte metabolism, gene expression and cytokine production following transdermal interactive neurostimulation(InterX), Gail Pyne-Geithman, Joseph F. Clark, Paul Magee

REFERENCE LITERATURE 
Non- Invasive Interactive Neurostimulation ” (NIN) InterX therapy

Criteria-Based Management of an Acute Multistructure Knee Injury in a Professional Football PlayerA.J. Yenchak PT DPT CSCS, Kevin E Wilk PT DPT, Christopher A Arrigo PT MS, Charles D Simpson II PT DPT CSCS, James R Andrews MD. Journal of orthopaedic & sports physical therapy. Vol 41, Number 9, Sept 2011Knee injury professional football player A Case Report

Results of a RCT using non-invasive interactive neurostimulation in the post-surgical recovery of patients with trochanteric fracture of the femur Gorodnichenko A.I., MD, Gorodetskyi I.G., Ph.D. Department of Traumatology and Orthopaedics, Scientific Educational Medical Centre, Federal Government Institution of the President of the Russian Federation, Moscow, RU, Journal of Bone and Joint Surgery  British Volume, Vol 89-B, Issue 11, 1488-1494 2007.

Changes in Lymphocyte Metabolism, Gene Expression and Cytokine production following Transdermal Interactive Neurostimulation:indicators of Connective Tissue Healing and Anti-inflammatory activity Joseph F.Clark, ATC, PhD. Gail Pyne-Geithman, D Phil Department of Neurology, University of Cincinnati, OH 45267-0536, USA. Read article

New physiological study defining the difference between the InterX and electro stimulation technologies has been carried out at the University of Cincinnati. These initial findings have provided some extremely valuable data as we continue our research into the mechanism of action and physiological effects of InterX Therapy. It explains the impact on the immune system and reparative mechanisms. Read abstract article

Influence of Neurostimulation in a Transected Medial Collateral Ligament in Sheep Bill Walsh, Director,Surgical & Orthopaedic Research Laboratories, University of New South Wales. Reported at the 6th Combined Meeting of the Orthopaedic Research Societies, October 2007, Honolulu, Hawaii. Read abstract article

The effects of a handheld, cutaneous, portable, neuro stimulator in patients with chronic severe orthopedic pain. Maale G, Gamez M. [poster]  18th Annual Symposium of the International Society for Technology in Arthroplasty, Kyoto, Japan 2005.  [presentation] 43rd Orthopedic and Trauma Congres, Buenos Aires, Argentina. December 2006 http://www.ista.to; P16-9, p. 143

Knee Injuries InterX therapy to solve unresolved sport injuries Coleman S. [presentation] International Congress on Sports Rehabilitation and Traumatology, Bologna, Italy, 2005.

Patient Treatment Experience (120 patients treated with acute and chronic pain), Technical File for CE Mark submitted by Neuro Resource Group, Inc. ISO 13485:2003, Certification # SM88698, October 2004.

Use of Noninvasive Interactive Neurostimulation to Improve Short-Term Recovery in Patients with Surgically Repaired Bimalleolar Ankle Fractures: A Prospective, Randomized Clinical Trial Igor G. Gorodetskyi, MD1, Anatolyi I. Gorodnichenko, MD1, Petr S. Tursin, MD1, Vitalyi K. Reshetnyak, MD2, Oleg N. Uskov, MD3 Read abstract article¦



Reference articles to study the importance of the skin impedance changes in responds to trauma, pain or inflammation

Cutaneous patterns of sympathetic activity in clinical abnormalities of the musculoskeletal system. Korr IM, Wright FM, Chace JA. In: Peterson B, ed. The collected papers of Irvin M Korr.  American Academy of Osteopathy, Colorado, 1964:66-72.

Using localized impedance measurements to study muscle changes in injury and disease. Aaron R, Shiffman CA. Ann of the NY Ac of Sc, 2000;904:171-180.

An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle. Jay Shah, Terry Phillips, Jerone Danoff and Lynn Gerber J Appl Physiol 99: 1977-1984, 2005

The Evaluation of Electrodermal Properties in the Identification of Myofascial Trigger Points Sarah P. Shultz, MEd, Jeffrey B. Driban, MEd, Charles B. Swanik, PhD June 2005

Biomedical Acupuncture for Pain Management; An Integrative Approach. Yun-tao Ma; Mila Ma; and Zang Hee Cho; 2005.

Trigger points and acupuncture points for pain: correlations and implications.Melzack R,Stillwell DM.;Pain. 1977 Feb;3(1):3-23.

Efficacy of electrical nerve stimulation for chronic musculoskeletal pain: a meta-analysis of randomized controlled trials. Johnson M, Martinson M. Pain. 2007 Jul;130(1-2):1-3. : 157-65. Epub 2007 Mar 23.

Effect of electrical stimulation on musculoskeletal systems; a meta-analysis of controlled clinical trials. Akai M, Hayashi K. Bioelectromagnetics. 2002 Feb;23(2):132-43.

From the Gate to the neuromatrix  Melzack R [Department of Psycology, McGill University, Montreal, Quebec, Canada] Pain. 1999 Aug; Suppl 6:S121-6.

The neuro-immuno-cutaneous-endocrine network: relationship of the mind and skin.O’Sullivan RL, Lipper G, Lerner EA. Arch Dermatol 1998;134:1431-1435.

Fall of skin impedance and bone and joint pain. Fujita T, Fujii Y, Okada S, Miyauchi A, Takagi Y. at all Journal of bone and mineral metabolism 1988 review.

Central effect of SCENAR application:  Self-restoration of an organism through activation of the front hypothalamus. Chebkasov SA, Bereshpolova UI SCENAR -Therapy, SCENAR Expertise, Taganrog 2000;7:15-21. (Russian)

Biomechanics of musculoskeletal pain: dynamics of the neuromatrix, Partap S. Khalsa [Department of Biomedical Engineering, State University of New York at Stony Brook, HSC T18-030 Stony Brook, NY 11794-8181,USA  Review

Skin Neuroendocreen Organ“ Dirk Roosterman, Tobias Goerge, Stefan W. Schneider, Nigel W. Bunnett and Martin Steinhoff PDF(1024KB)

Evaluation of Electrodermal properties in the identification of myofascial trigger points“ Sarah P. Shultz, Jeffrey B. Driban, Charles B. Swanik PDF(152KB)

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